The FIGHT study (FPA144-004; NCT03343301) is a global, randomized, double-blind, placebo-controlled phase 3 trial evaluating FOLFOX6 with FPA144 as first-line treatment in patients with advanced GC harboring FGFR2b overexpression or FGFR2 amplification. Here, FGFR2 is linked to gastric cancer.