Numerous lncRNAs such as H19 (Ohtsuka et al., 2016), CCAT1 (McCleland et al., 2016), HOTAIR (Kogo et al., 2011), MALAT-1 (Ji et al., 2014), DACOR1 (Shi et al., 2015), and PVT-1 (Takahashi et al., 2014) are dysregulated in CRC and may serve as therapeutic targets for CRC. The gene discussed is PVT1; the disease is colorectal carcinoma.