The overexpression of LINC00460 could promote cell proliferation and invasion in lung cancer (Li et al., 2018; Ye et al., 2019), gastric cancer (Wang F et al., 2018), ovarian cancer (Liu X et al., 2018), esophageal cancer (Liu W et al., 2018), and gefitinib resistance in nonsmall cell lung cancers (Ma et al., 2019), thus suggesting its carcinogenic effect. The gene discussed is LINC00460; the disease is esophageal cancer.