Premutations of the FMR1 gene involving 55–200 CGG repeats also confer risk for multiple subclinical issues as well as medical, psychiatric, and neurodegenerative conditions (Lozano et al., 2014) including fragile X-associated tremor/ataxia syndrome (FXTAS). This evidence concerns the gene FMR1 and fragile X-associated tremor/ataxia syndrome.