ADNP and Alzheimer disease: Subsequent studies have shown that ADNP is dysregulated in schizophrenia (Dresner et al., 2011; Merenlender-Wagner et al., 2015) and Alzheimer’s disease (AD) (Yang et al., 2012; Malishkevich et al., 2016), and mutated in autism spectrum disorder (ASD) with 0.17% prevalence (together, these ASD cases are now identified as the ADNP syndrome) (Helsmoortel et al., 2014; Gozes et al., 2015).