ALB and hydrops fetalis: Previous studies examining the effects of HF diet on the hippocampal BBB have reported increased permeability to circulating compounds (e.g., fluorescein, Evans blue, albumin, IgG) in rodents fed the diet over a 2–4 months period (Kanoski et al., 2010; Davidson et al., 2012; Pallebage-Gamarallage et al., 2012; Hargrave et al., 2016; Hajiluian et al., 2017; Mamo et al., 2019; Salameh et al., 2019).