CD4 and Alzheimer disease: One such cytokine, thymic stromal lymphopoetin (TSLP) is a key inducer of the Type two immune response, which is characteristic of human AD and the MC903 model, via signaling in CD4+ T cells, basophils, and other immune cells (Li et al., 2006; Zhang et al., 2009; Briot et al., 2010; Demehri et al., 2009; Gao et al., 2010; Kim et al., 2013).