Myocardial apoptosis is mainly responsible for myocyte loss post‐MI and is considered the key link of ventricular remodelling.31, 32 We performed various techniques, such as TUNEL, flow cytometry, Western blot, CCK8 and LDH assays in order to demonstrate that inhibition of lncRNA MEG3 could protect against hypoxia‐induced apoptosis in cultured NMVMs and infarct hearts. This evidence concerns the gene MEG3 and myocardial infarction.