MEG3 and myocardial infarction: Ventricular remodelling following MI is characterized by cardiomyocyte loss, compensatory myocardial hypertrophy and cardiac fibrosis, resulting in changes in the size, shape and function of the heart.19, 20, 21 In the present study, the heart tissues from the lenti‐si lncRNA MEG3 group exhibited less spherical shape than those from the lenti‐GFP group at 4 weeks post‐LAD ligation in gross specimen (Figure 2A).