SIRT3 and atherosclerosis: Sirtuin 3 (Sirt3), a member of the nicotinamide adenine dinucleotide-dependent histone deacetylase sub-family, has been identified as a key regulator of mitochondrial fission in several inflammation-related diseases, including high fat diet-induced hepatic inflammation [23], wound repair [24], atherosclerosis-related endothelial cell dysfunction [25], and diabetic cardiomyopathy [26].