KLK14 and posterior cortical atrophy: Finally, because KLK14 was found to be elevated in PCa metastases compared to primary prostate tumors (Fig. 1B) and PCa primarily metastasizes to bone forming mostly osteoblastic lesions, we also performed a migration assay with iGFP‐, imKLK14‐, and iKLK14‐LNCaP cells on a novel OBM live model mimicking osteoblastic mineralized tissue from the bone microenvironment ((Bock et al., 2019), Fig. 6C top panel).