Thus, the term H‐type hypertension was proposed, which was defined as hypertension together with hyperhomocysteine more than 10 μmol/L.12, 13 Numerous studies have found that H‐type hypertension increased the risk of ischemic stroke compared with non‐H‐type hypertension.14, 15 Although a relationship between Lp‐PLA2 level and ischemic stroke has been demonstrated by several studies,8, 16 the relationship between serum Lp‐PLA2 levels and H‐type hypertension in patients with ischemic stroke remains poorly understood. This evidence concerns the gene PLA2G7 and hypertensive disorder.