The multivariate logistic regression results showed that a Lp‐PLA2 concentration >208.46 mg/L was finally included in the model as an independent variable associated with patients with ischemic stroke with H‐type hypertension (OR: 2.560, 95% CI: 1.085‐6.040, P = .032). The gene discussed is PLA2G7; the disease is ischemic stroke.