Among PCOS patients, the power of serum ICAM-1 (ng/ml) levels in discriminating T2DM from NGT, the AUC was 0.956 (95% CI = 0.933–0.986) with sensitivity = 93.3%, specificity = 82.9%, and the cutoff values (121.2). The gene discussed is ICAM1; the disease is type 2 diabetes mellitus.