ROC analysis revealed that combined serum and expression levels of ICAM-1 to discriminate PCOS from control, the AUC was 0.963 (95% CI = 0.937–0.988, P < 0.001) with sensitivity = 98.1%, specificity = 69.9% (Fig. 3c). The gene discussed is ICAM1; the disease is polycystic ovary syndrome.