The genetic study for FMF, TNF receptor-associated periodic syndrome (TRAPS), Mevalonate kinase deficiency (MVK) documented the presence of the MEFV gene heterozygous mutations E148Q (exon 2), P369S, R408Q (exon 3) in the child, in the sibling, in the 6-years-old brother and in the father. This evidence concerns the gene MEFV and mevalonate kinase deficiency.