In particular, TRPC6 and TRPV6 have recently been reported to play a critical role in the development of many carcinomas including human hepatocellular carcinoma [25], renal cell carcinoma [26], prostate cancer [21], lung cancer [27], and other types of cancer [23,28,29,30,31,32]. The gene discussed is TRPC6; the disease is Familial prostate cancer.