On the contrary, forced miR-29b expression inhibits osteoclast markers nuclear factor of activated T-cell, cytoplasmic 1 (NFATc1) and matrix metallopep (MMP9) expression and also reduces collagen degradation and pit formation of osteoclastic cultures in a multiple myeloma-mediated osteolysis model [32]. This evidence concerns the gene MMP9 and plasma cell myeloma.