After adjustments in the multivariable analyses (included variables: sex, age, body mass index, estimated glomerular filtration rate, type of surgery, urgent surgery, ejection fraction, pulmonary hypertension, acute coronary syndrome, liver disease, statin, alcohol consumption, albumin, and bilirubin), the low ALT and high De Ritis ratio categories were determined to be independently associated with increased 90-day mortality risk (Table 3 and Figure 2). The gene discussed is GPT; the disease is pulmonary arterial hypertension.