On the other hand, high expression of BIRC5 expression increased resistance of ccRCC cell lines to drugs such as Salubrinal, PHA-665752, GNF-2, Imatinib, Nilotinib, and Selumetinib (p < 0.05), and increased sensitivity of ccRCC cell lines to other drugs such as CGP-60474, BMS-536924, JW-7-52-1, Panobinostat, Dasatinib, WH-4-023, Rapamycin, Saracatinib, and Bryostatin 1(p < 0.05; Figure 9B). The gene discussed is BIRC5; the disease is nonpapillary renal cell carcinoma.