GAS5 and ischemic stroke: GAS5 plays a regulatory role in pathophysiological process of liver fibrogenesis,22 tumorigenesis and metastasis,25 ischaemic stroke,26 etc Liu SD et al found that overexpression of GAS5 promoted myocardial apoptosis in H/R‐exposed cardiomyocyte,8 but whether down‐regulation of GAS5 alleviates myocardial I/R injury is not determined in their study.