DDIT3 and Hyperglycemia: For example, a study showed that hyperglycemia aggravated hepatic warm ischemia and reperfusion injury by inducing hyperinflammatory immune responses via the activation of the AGE‐RAGE signaling pathway in KCs.34 Another study showed that hyperglycemia aggravated hepatic warm ischemia and reperfusion injury by inhibiting liver‐resident macrophage M2 polarization via C/EBP homologous protein‐mediated endoplasmic reticulum stress.5 However, the effects of hyperglycemia on TAA‐induced liver injury remain largely unknown.