CREB1 and Alzheimer disease: Interestingly, we observed that the phosphorylation level of CREB‐1 was also increased in hippocampal slices co‐treated with miR‐134i and Aβ (1–42) (Figure 5a, 5, one‐way ANOVA, p = .0007), indicating a novel miR‐134‐CREB‐BDNF mechanism in rescuing late‐LTP and STC impairment in Aβ‐induced AD condition.