CYP2R1 and non-small cell lung carcinoma: Based on the results of a genome-wide association study (GWAS) [11] and analysis of bioinformatics data, our previous research selected several SNPs which are either potentially functional or known as tagSNPs in the CYP2R1, CYP27B1, CYP24A1, GC and VDR genes, and analyzed their genotypes in 1264 case and control subjects to determine their association with NSCLC.