For example, the presence of IL‐17‐producing γδ T cells in colon cancer has been associated with poor prognosis.37, 110 Interestingly, though a pan‐cancer analysis of the TCGA database identified a combined Th1/Th17 immune signature as the most beneficial for patient survival, this group showed the most pronounced Th17 gene signature but appeared balanced by the presence of a Th1 response.111 This study requires further dissection to determine the relative contribution of Th1 and Th17 genes to this signature. Here, IL17A is linked to cancer.