The authors proposed that, while NKG2D has evident antitumor function in early stages of cancer, it could exacerbate the pro‐inflammatory microenvironment of the tumor at later stages, leading to tissue damage and enhanced cell proliferation, which promoted tumor progression in the liver environment.55 While the authors did not look at the implication of γδ T cells in this process, these cells could nevertheless play a role, given their enrichment in the liver and their robust cytokine expression in response to many inflammatory signals.56 Here, KLRK1 is linked to neoplasm.