Expansion with NKF cells also led to an increase in adhesion receptors (LFA-1 and CD54) which are important for NK cell conjugation with tumor targets, enhancing cytolysis (Fig. 3C and Supplemental Fig. 4) CD57 expression, denoting terminal differentiation of NK cells, was also measured and found to be decreased in NKF-NK cells (Fig. 3D). The gene discussed is ICAM1; the disease is neoplasm.