While it is possible that reduced GFR may lead to altered renal handling of IgG and affect levels of circulating autoantibodies, we did not observe any relationship with total IgG against malaria antigens AMA-1, MSP-1, CSP, or GLURP and any measures of renal function (AKI, creatinine, BUN, or eGFR). The gene discussed is DNAJC5; the disease is malaria.