However, other study have showed that low CD4+ T cell count was not major risk factor for Blastocystis infection [27], for instance, no significant differences of Blastocystis infection was observed in HIV/AIDS individuals with or without CD4+ T cell count more than 200 cells/μl [7], and another study showed that compared to HIV/AIDS patients with CD4+ T cell count less than 50 cells/μl, patients with CD4+ T cell count more than 50 cells/μl were not more likely to be infected by Blastocystis [28]. The gene discussed is CD4; the disease is Blastocystis infectious disease.