PGR and neoplasm: These results allow the further development of the delivery strategy by changing either the type of Au-NP (size and geometry) for applications as photothermal therapy or to decorate the surface of the nanoparticle with signaling and targeting proteins able to direct the Au-NPs to G protein-coupled receptors (estrogen and progesterone receptors) of tumor cells or to specific organelles such as mitochondria or Golgi within cancer cells or cells suffering dysfunction related to these organelles.