CD86 and Peripheral demyelination: Considering the distinct M/M polarization patterns between LPC- and LPS-induced demyelination, correlations between OD ratio and M1 (CD16/32+Iba1+ or CD86+Iba1+) and M2 (CD206+Iba1+ or Arg1+Iba1+) proportions were calculated in LPC and LPS groups, respectively (Fig. 9b, c).