Interestingly, circPLEKHM3 expression was further decreased in peritoneal metastatic ovarian carcinomas as compared with the primary ovarian carcinomas they were derived from, whereas PLEKHM3 expression did not differ between metastatic and primary carcinomas (Fig. 1f and Additional file 8: Figure S5). The gene discussed is PLEKHM3; the disease is ovarian carcinoma.