CRP and systemic inflammatory response syndrome: There have been many clinical scoring systems proposed to predict severity in the early phase of AP (Ranson [4], Modified Glasgow [5], Systemic Inflammatory Response Syndrome (SIRS) [6], and Acute Physiology, Age, Chronic Health Evaluation II (APACHE II) [7]), together with imaging-guided severity indexes (Balthazar [8], computed tomography severity index [9]), or even single laboratory parameters such as C-reactive protein, procalcitonin or blood urea nitrogen.