(4) Indication of IGF2 as one of the panels of several CIMP-specific markers (together with CACNA1G, NEUROG1, RUNX3, SOCS1, CDKN2A, CRABP1, and MLH1) in diagnostics of chromosomal instability (CIN) or CpG island methylator phenotype (CIMP) in colorectal tumors;. The gene discussed is IGF2; the disease is cervical squamous intraepithelial neoplasia.