Furthermore, four (BUB1, RAN, REL, and RPS19) of the target genes were strictly oncogenic in nature showing that BUB1 [50,51] and RPS19 [52] were up-regulated and RAN [53], and REL [54] were down-regulated in solid tumors including CRC (Figure 3). The gene discussed is RPS19; the disease is colorectal carcinoma.