Furthermore, they have high levels of amidated gastrin’s, which are the form that causes acid secretion and ECL cell changes [24,39], as well as incompletely processed gastrin forms progastrin, and glycine-extended precursors, which are the forms that are reported to have growth affects in the colon, a number of other tissues and in other various tumors including colon cancer, although the latter points are controversial [21,24,39,78,89,90,91]. The gene discussed is GAST; the disease is colonic neoplasm.