Using Western blot we confirmed further corroborate the decrease in transferrin in serum of lung cancer patients after a second cycle of chemotherapy (Fig 3A); an increase in content of fibrinogen α chain in lung patients before and after second cycle of chemotherapy (Fig 3B) and decrease in the content of vitronectin in serum of lung cancer patients before chemotherapy in relation to SCC and ADC (Fig 3C). This evidence concerns the gene TF and lung cancer.