LCORL has been linked to arginine metabolism in growth[34] and can interact with C-terminal binding protein 1 (CTBP1), another transcriptional regulator.[35] A marker within another C-terminal binding protein (CTBP2) has been significantly associated with canine hip dysplasia using two mapping methods.[17,20] The locus CFA24:26793945 also had a large effect size (Table 6). Here, LCORL is linked to Hip dysplasia.