SASH1 and cancer: Among the 14 overlapped genes, FAM84A, localized in the subcellular membrane region, was involved in invasion and/or metastasis of colon cancer cells influencing colorectal cancer [57]; SASH1 was a member of the SH3-domain containing expressed in lymphocytes (SLY1) gene family, it encodes signal adapter proteins which were composed of certain protein–protein interaction domains, showing prognostic significance in human cancer [58].