NFKBIZ and psoriasis: Furthermore, whereas psoriasis-related genes, such as Cxcl2, Cxcl1, and Il1f6, were significantly induced in the skin of K14-IL17Aind Ctrl mice, the same genes were expressed neither in skin samples (Figure 5F) nor in keratinocytes isolated from mice harboring an additional deletion of IκBζ in keratinocytes (Figure 5G).