Among others, important psoriasis-associated target genes of IκBζ include certain chemo- and cytokines (e.g., Cxcl1, Cxcl2, Cxcl5, Ccl3, and Il17c) as well as antimicrobial proteins, such as S100 calcium-binding proteins (e.g., S100a9), β-defensin-2 (Defb4), and lipocalin-2 (Lcn2). The gene discussed is S100A9; the disease is psoriasis.