All the CA3 (PSD95‐cTAP; Grik4 Cre) enriched proteins (Abr, Actn4, Bai3, Cacng8, Grik2, Hist1h2al, Mbp, Nlgn3 and Prdx5) have been reported to have important functions in brain that include roles in synapse formation, synaptic plasticity and psychiatric disorders (Duman, Tu, & Tolias, 2016; Ge et al., 2016; Kalinowska et al., 2015; Lanoue et al., 2013; Malty et al., 2017; Martinelli et al., 2016; Oh et al., 2010; Park et al., 2017; Sigoillot et al., 2015; Walikonis et al., 2001; Yamagata et al., 2017). This evidence concerns the gene GRIK2 and psychiatric disorder.