The factors consistently and independently associated with HHV infections were male sex, older age, being married, high HIV viral load, mother‐to‐child transmission of HIV, and current use of HAART regimen using PIs instead of NNRTIs.22 The relationship between different HHV infections and immune status, WHO HIV clinical stage, and HIV infection duration were not shown in multivariate analysis, in spite of CD4 counts that were significantly associated with the detection of EBV and HHV‐7 in univariate analysis. The gene discussed is CD4; the disease is HIV infectious disease.