These phenomena were probably due to the younger average age at marriage, lower socioeconomic status, crowded living conditions, poor hygiene,23 and high levels of concomitant HIV infection in male partners, which may enhance HHVs infectivity of those partners.24 Plasma HIV viral load, CD4 count, and HAART therapy influenced each case of herpesvirus infection in different ways.5, 25 No significant correlations were observed between the rate of HHV shedding and CD4 cell count or plasma HIV‐1 RNA level among the HAART‐treated patients of previous studies26, 27 and our study. The gene discussed is CD4; the disease is HIV infectious disease.