CEACAM5 and colonic neoplasm: As a result, LNM [subdistribution hazard ratio (SHR) = 2.96, P < 0.001], tumor size > 3.0 cm (SHR = 1.50, P = 0.026), negative CEA level (SHR = 0.45, P < 0.001), poorly differentiated (SHR = 1.60, P < 0.031) or undifferentiated (SHR = 2.91, P = 0.022) carcinoma, diagnosis during 2010–2012 (SHR = 0.60, P = 0.001), older age (SHR = 1.61, P = 0.048 for age 65–79 years; SHR = 3.01, P < 0.001 for age over 80 years), white ethnicity (SHR = 0.57, P < 0.001), and single/widowed marital status were all significant prognostic factors for T1 colon cancer (Table 6).