Among 21 adverse events in the HK L-137 group, there were four of influenza, four of common cold symptoms, two of inflammatory symptoms, two of digestive symptoms, one of pruritus, one of palpitations, three of high creatine kinase levels, one of a high uric acid level, one of a high insulin level, one of high urinary protein, and one of hypertension. The gene discussed is INS; the disease is hypertensive disorder.