TGFB3 and myocardial infarction: Genetic disruption of the chemokine monocyte chemoattractant protein (MCP)-1/CCL2, a mediator with a crucial role in recruitment of monocytes/macrophages in inflamed tissues, was associated with reduced TGF-β2 and TGF-β3 mRNA expression following myocardial infarction, consistent with an important role for infiltrating mononuclear cells in TGF-β synthesis in the infarcted heart (17).