IGHE and atopic eczema: The majority of disorders involving non-IgE-mediated CMPA are localized to the gastrointestinal tract (nausea, vomiting, diarrhea, abdominal pain, blood in stool malabsorption, and failure to thrive or weight loss), and in some cases, atopic dermatitis symptoms may present at the same time (Table 1) (28, 50).