Decreased SNHG12 expression by SNHG12 interference sequences in the cancer cell lines, TPC-1, and BCPAP, resulted in decreased proliferative capacity, an increased apoptotic rate (~28% increase in K1 and >28% in TPC-1), and impaired metastatic and migration capacities, implicating SNHG12 in tumor cell proliferation. The gene discussed is SNHG12; the disease is cancer.