Subgroup analysis regarding the tumor location showed that high-PD-L1 expression in TCs had no significant association with OS (OS for iCCA: HR = 1.32, 95% CI [0.50–3.50], p = 0.581; eCCA: HR = 1.32, 95% CI [0.58–3.01], p = 0.514; iCCA+ eCCA mixed: HR = 3.17, 95% CI [0.63–15.91], p = 0.162). The gene discussed is CD274; the disease is neoplasm.