EGF and malignant colon neoplasm: They reported that many human cancers exhibit higher C1QBP expression levels than their nonmalignant histologic counterparts, including thyroid, lung, esophagus, gastric and colon cancer and referred to that previous reports have confirmed that C1QBP mediates epidermal growth factor (EGF)-induced cancer cell chemotaxis and distant metastasis by activation of receptor tyrosine kinases.