Analyzing gene expression of C1-INH in the pancreatic cancer cell lines from Dasatinib sensitive versus resistant pancreatic tumor cells lines using mRNA transcripts showed that C1-INH was significantly upregulated in Dasatinib sensitive versus resistant tumor cell lines (p-value 0.004, fold change 2), with a higher expression of C1-INH in the sensitive cell lines as compared to the resistant ones (Figure 5). Here, SERPING1 is linked to familial pancreatic carcinoma.