To date, 13 NAT derivatives and their analogs have been isolated since the 1960s, which exhibit various biological activities of immunosuppression, anti-microbial, fungicidal, and anti-tumor effects (Li et al., 2013; Salim et al., 2014; Lim et al., 2016; Zhou et al., 2018). The gene discussed is BRD2; the disease is neoplasm.