PPP1R1B and schizophrenia: In PFC, the ratio of DARPP-32/CaN in each sample were significantly low in schizophrenia patients compared to controls (t [29.72] = 4.45, p = 1.12e-4) (Fig. 3b), but no changes were observed in NAc (t [33.71] = −0.185, p = 0.854) (Fig. 3d).