VTCN1 and neoplasm: All tumors and adjacent organ of three groups were detected clearly on T1WI and T2WI images, observed isointensity on T1WI images, hyperintensity and more hyperintensity in necrotic areas on T2WI; In addition, the B7-H4 siRNA-2 group exhibited a major decrease of tumor volume on Coronal T2WI plus fat repression compared with non-target siRNA group and blank control group.