MALAT1 and Myocardial fibrosis: Furthermore, a previous study indicated that lncRNA MALAT1 could induce myocardial fibrosis [20] and pulmonary vascular remodeling of pulmonary artery hypertension [21]; however, the effects of lncRNA MALAT1 on thoracic aorta and myocardial remodeling of hypertensive rats remain to be explored.