KLK3 and posterior cortical atrophy: Despite this, administration of the humanized bispecific antibody MOR209/ES414 in murine xenograft models of human PCa led to the inhibition of tumor growth and increased survival, decreasing PSA expression only in adoptively transferred human T cells [90] A phase I study is ongoing to identify the maximum tolerated dose and to test the clinical activity of ES414 in mPCa patients [NCT02262910].