ICAM1 and ganglioneuroma: RNAseq analysis (Fig. 3 A) showed remarkably decreased ICAM1 transcription levels in GN-DU145 cells compared with those in WT- and GFP-DU145 cells; according to these results, histone H3 lysine 27 acetylation (H3K27Ac), a known transcription activation marker, was decreased on the ICAM1 gene in GN-DU145 cells (Fig. 5 B).